Immunogenicity testing and protein engineeringAntitope is pioneering a new generation of immunogenicity testing, antibody humanization and protein engineering technologies. Our mission is to apply these technologies to create improved non-immunogenic biologics.Formed in 2004, Antitope offer proprietary technologies as a comprehensive service for evaluating immunogenicity, identifying T cell epitopes, producing humanized antibodies and generating non-immunogenic proteins. The core proprietary technologies include: EpiScreen™ for accurately measuring the immunogenicity potential of therapeutic proteins and different formulations, identifying specific T cell epitopes or determining the potential of NCEs to induce late onset allergy like reactions. Composite Human Antibodies™ to generate humanized, T cell epitope depleted antibodies for therapeutic use. Composite Proteins™ to generate non-immunogenic proteins with desired biological function for therapeutic use. |